Enantioselective nitrone cycloadditions of alpha,beta-unsaturated 2-acyl imidazoles catalyzed by bis(oxazolinyl)pyridine-cerium(IV) triflate complexes.

نویسندگان

  • David A Evans
  • Hyun-Ji Song
  • Keith R Fandrick
چکیده

[Structure: see text] Enantioselective nitrone cycloadditions with beta-substituted alpha,beta-unsaturated 2-acyl imidazoles catalyzed by bis(oxazolinyl)pyridine-cerium(IV) triflate complexes 1 have been reported. The isoxazolidine products were efficiently transformed into densely functionalized beta'-hydroxy-beta-amino acid derivatives.

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عنوان ژورنال:
  • Organic letters

دوره 8 15  شماره 

صفحات  -

تاریخ انتشار 2006